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Literature summary extracted from

  • Reina-Pinto, J.; Voisin, D.; Kurdyukov, S.; Faust, A.; Haslam, R.; Michaelson, L.; Efremova, N.; Franke, B.; Schreiber, L.; Napier, J.; Yephremov, A.
    Misexpression of fatty acid elongation1 in the Arabidopsis epidermis induces cell death and suggests a critical role for phospholipase A2 in this process (2009), Plant Cell, 21, 1252-1272.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.199 additional information not inhibited by aristolochic acid Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.199 Arabidopsis thaliana
-
 ecotype Columbia
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.199 epidermis
-
 Arabidopsis thaliana
-
2.3.1.199 seed FAE1 is a seed-specific enzyme Arabidopsis thaliana
-
2.3.1.199 trichome
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.199 very-long-chain acyl-CoA + malonyl-CoA
-
 Arabidopsis thaliana CoA + very-long-chain 3-oxoacyl-CoA + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.199 beta-ketoacyl-CoA synthase
-
 Arabidopsis thaliana
2.3.1.199 FAE1
-
 Arabidopsis thaliana
2.3.1.199 fatty acid elongation1
-
 Arabidopsis thaliana
2.3.1.199 KCS
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.3.1.199 malfunction FAE1 misexpression plants are similar to the wild type but display an essentially glabrous phenotype, owing to the selective death of trichome cells. Nuclei of arrested trichome cells in FAE1 misexpression plants cell-autonomously accumulate high levels of DNA damage, including double-strand breaks characteristic of lipoapoptosis Arabidopsis thaliana
2.3.1.199 physiological function enzymic activity of FAE1 is required to suppress trichome development. The enzyme plays a role in the biosynthesis of cutin Arabidopsis thaliana