Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Bonza, M.C.; De Michelis, M.I.
    The plant Ca2+-ATPase repertoire: biochemical features and physiological functions (2011), Plant Biol., 13, 421-430.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.2.2.10 Calmodulin auto-inhibited Ca2+-ATPase Arabidopsis thaliana

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.10 cyclopiazonic acid inhibitor of ER-type Ca2+-ATPases Arabidopsis thaliana
7.2.2.10 eosin Y auto-inhibited Ca2+-ATPases are particularly sensitive to inhibition by eosin Y Arabidopsis thaliana
7.2.2.10 erythrosin B auto-inhibited Ca2+-ATPases are particularly sensitive to inhibition by erythrosin B Arabidopsis thaliana
7.2.2.10 La3+
-
 Arabidopsis thaliana
7.2.2.10 orthovanadate
-
 Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.2.10 Golgi apparatus isoform ECA3 Arabidopsis thaliana 5794
-
7.2.2.10 membrane
-
 Arabidopsis thaliana 16020
-
7.2.2.10 plasma membrane isoform ACA9 Arabidopsis thaliana 5886
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.2.2.10 Ca2+
-
 Arabidopsis thaliana
7.2.2.10 Mn2+ ER-type Ca2+-ATPases can transport, beside Ca2+, also Mn2+ and Zn2+ ions Arabidopsis thaliana
7.2.2.10 Zn2+ ER-type Ca2+-ATPases can transport, beside Ca2+, also Mn2+ and Zn2+ ions Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.10 Arabidopsis thaliana
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
7.2.2.10 phosphoprotein auto-inhibited Ca2+-ATPase Arabidopsis thaliana

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.10 pollen isoform ACA9 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.10 ATP + H2O + Ca2+/out
-
 Arabidopsis thaliana ADP + phosphate + Ca2+/in
-
 ?
7.2.2.10 additional information ER-type Ca2+-ATPases show a strong preference for ATP as substrate. Conversely, auto-inhibited Ca2+-ATPases are able to use ITP or GTP as an alternative to ATP Arabidopsis thaliana ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.10 ACA
-
 Arabidopsis thaliana
7.2.2.10 auto-inhibited Ca2+-ATPase
-
 Arabidopsis thaliana
7.2.2.10 Ca2+-ATPase
-
 Arabidopsis thaliana
7.2.2.10 Ca2+-pumping ATPase
-
 Arabidopsis thaliana
7.2.2.10 eCA
-
 Arabidopsis thaliana
7.2.2.10 ER-type Ca2+-ATPase
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
7.2.2.10 malfunction knock-out mutants of isoform ACA9 displays reduced growth of pollen tubes, with high frequency of aborted fertilization leading to a 3fold reduction in seed set. Knock-out mutants of isoforms ACA8 or ACA10 do not have an altered phenotype, with a noticeable exception: knock-out of ACA10 in a genotype containing a naturally occurring dominant allele of an unlinked gene causes altered adult vegetative development and the formation of floral clusters. Isoform ECA1 knock-out mutant is indistinguishable from the wild type, but it clearly shows reduced root growth and toxicity symptoms when exposed to 0.5 mM Mn2+. An ECA3 knock-out mutant is not more sensitive than the wild type to Mn2+ toxicity, but rather requires higher Mn2+ concentrations for growth. Both isoform ECA1 and ECA3 knock-out mutants have slightly altered Ca2+ sensitivity Arabidopsis thaliana
7.2.2.10 physiological function Ca2+-ATPases use the energy of ATP hydrolysis to pump Ca2+ from the cytoplasm into intracellular compartments or into the apoplast. Ca2+-ATPases play an important role in maintenance of cytoplasmic Ca2+ homeostasis. Isoform ECA3 may also play an essential role in Mn2+ nutrition. Plasma membrane-localized auto-inhibited Ca2+-ATPases are also involved in the response to pathogens, hormonal regulation, salt stress, and cold stress Arabidopsis thaliana