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Literature summary extracted from

  • Xu, H.; Aurora, R.; Rose, G.D.; White, R.H.
    Identifying two ancient enzymes in Archaea using predicted secondary structure alignment (1999), Nat. Struct. Biol., 6, 750-754.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.105 expression in Escherichia coli Methanocaldococcus jannaschii

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.105 33076
-
 x * 33076, calculated from sequence Methanocaldococcus jannaschii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.105 (7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate Methanocaldococcus jannaschii the enzyme is involved in the biosynthesis of methanopterin N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.105 Methanocaldococcus jannaschii Q57749
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.105 recombinant protein Methanocaldococcus jannaschii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.105 (7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate
-
 Methanocaldococcus jannaschii N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
-
 ?
2.5.1.105 (7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate the enzyme is involved in the biosynthesis of methanopterin Methanocaldococcus jannaschii N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
-
 ?
2.5.1.105 6-hydroxymethyl-7,8-dihydropterin diphosphate + 1-(4-aminophenyl)-1-deoxy-D-ribitol about 25% of the activity compared to 4-(beta-D-ribofuranosyl)aminobenzene-5'-phosphate Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol + diphosphate
-
 ?
2.5.1.105 additional information no activity with 4-(beta-D-ribofuranosyl)-aminobenzene Methanocaldococcus jannaschii ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.105 ? x * 33076, calculated from sequence Methanocaldococcus jannaschii

Synonyms

EC Number Synonyms Comment Organism
2.5.1.105 dihydropteroate synthase ambiguous Methanocaldococcus jannaschii
2.5.1.105 MJ0301
-
 Methanocaldococcus jannaschii