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Literature summary extracted from

  • Teerawanichpan, P.; Qiu, X.
    Fatty acyl-CoA reductase and wax synthase from Euglena gracilis in the biosynthesis of medium-chain wax esters (2010), Lipids, 45, 263-273.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.42 expressed in Saccharomyces cerevisiae strain H1246 Euglena gracilis
2.3.1.75 expression in Saccharomyces cerevisiae Euglena gracilis

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.75 additional information co-expression of fatty acyl-CoA reductase and wax synthase in Saccharomyces cerevisiae results in synthesis of myristyl myristate, myristyl palmitoleate, myristyl palmitate and palmityl myristate when fed with myristic acid Euglena gracilis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.75 41200
-
 x * 41200, calculated Euglena gracilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.42 hexadecanoyl-CoA + NADPH + H+ Euglena gracilis 24% conversion efficiency hexadecanal + CoA + NADP+
-
 ?
1.2.1.42 tetradecanoyl-CoA + NADPH + H+ Euglena gracilis preferred substrate, 34% conversion efficiency tetradecanal + CoA + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.42 Euglena gracilis
-
-
-
2.3.1.75 Euglena gracilis D7PN09
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.42 hexadecanoyl-CoA + NADPH + H+ 24% conversion efficiency Euglena gracilis hexadecanal + CoA + NADP+
-
 ?
1.2.1.42 tetradecanoyl-CoA + NADPH + H+ preferred substrate, 34% conversion efficiency Euglena gracilis tetradecanal + CoA + NADP+
-
 ?
2.3.1.75 lauroyl-CoA + tetradecanol
-
 Euglena gracilis tetradecyl laurate + CoA
-
 ?
2.3.1.75 myristoyl-CoA + (9Z)-hexadec-9-en-1-ol
-
 Euglena gracilis (9Z)-hexadec-9-en-1-yl tetradecanoate + CoA
-
 ?
2.3.1.75 myristoyl-CoA + dodecan-1-ol
-
 Euglena gracilis dodecan-1-yl myristate + CoA
-
 ?
2.3.1.75 myristoyl-CoA + hexadecan-1-ol
-
 Euglena gracilis hexadecyl myristate + CoA
-
 ?
2.3.1.75 myristoyl-CoA + tetradecan-1-ol
-
 Euglena gracilis tetradecyl myristate + CoA
-
 ?
2.3.1.75 palmitoleoyl-CoA + tetradecanol enzyme shows preference towards myristic acid and palmitoleyl-CoA Euglena gracilis tetradecyl (9Z)-hexadec-9-enoate + CoA
-
 ?
2.3.1.75 palmitoyl-CoA + tetradecanol
-
 Euglena gracilis tetradecyl palmitate + CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.75 ? x * 41200, calculated Euglena gracilis

Synonyms

EC Number Synonyms Comment Organism
1.2.1.42 FAR
-
 Euglena gracilis
1.2.1.42 fatty acyl-CoA reductase
-
 Euglena gracilis

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.42 NADPH
-
 Euglena gracilis