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Literature summary extracted from
- Individualized therapy: Role of thiopurine S-methyltransferase protein and genetic variants (2010), J. Med. Biochem., 29, 150-155.
No PubMed abstract available
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 2.1.1.67 | medicine | thiopurine S-methyltransferase gene polymorphisms are pharmacogenetic markers which enable the individualization of thiopurine drug therapy | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.1.1.67 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.1.1.67 | K-562 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.1.1.67 | S-adenosyl-L-methionine + 6-mercaptopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + 6-methylmercaptopurine | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 2.1.1.67 | TPMT | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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