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Literature summary extracted from

  • Hall, A.M.; Kou, K.; Chen, Z.; Pietka, T.A.; Kumar, M.; Korenblat, K.M.; Lee, K.; Ahn, K.; Fabbrini, E.; Klein, S.; Goodwin, B.; Finck, B.N.
    Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver (2012), J. Lipid Res., 53, 990-999.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.22 Homo sapiens Q3SYC2
-
-
2.3.1.22 Homo sapiens Q86VF5
-
-
2.3.1.22 Homo sapiens Q96PD6
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.22 liver expression of MOGAT2 does not correlate with enzymatic activity Homo sapiens
-
2.3.1.22 liver expression of MOGAT3 is correlated with enzymatic activity Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.22 decanoyl-CoA + 2-oleoylglycerol
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.22 MGAT
-
 Homo sapiens
2.3.1.22 MOGAT1
-
 Homo sapiens
2.3.1.22 MOGAT2
-
 Homo sapiens
2.3.1.22 MOGAT3
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.22 additional information
-
 assay carried out at room temperature Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.22 7.4
-
 assay at Homo sapiens

Expression

EC Number Organism Comment Expression
2.3.1.22 Homo sapiens marked weight loss following gastric bypass surgery is associated with a significant reduction in MOGAT2 and MOGAT3 expression down

General Information

EC Number General Information Comment Organism
2.3.1.22 malfunction knockout of MOGAT3 attenuates MGAT activity in a liver-derived cell line Homo sapiens