EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.6.5.2 | GTP + H2O | Apis mellifera | - |
GDP + phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.6.5.2 | Apis mellifera | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.6.5.2 | brain | Rho GTPase activation in the worker honey bee brain | Apis mellifera | - |
3.6.5.2 | mushroom body | a transient increase in Rac activity coupled with a transient decrease in RhoA activity occurs in honey bees with 4 days foraging experience compared with same-aged new foragers | Apis mellifera | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.6.5.2 | GTP + H2O | - |
Apis mellifera | GDP + phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.6.5.2 | Rac | - |
Apis mellifera |
3.6.5.2 | RhoA | - |
Apis mellifera |
3.6.5.2 | small, monomeric G protein | - |
Apis mellifera |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.6.5.2 | evolution | Rac and RhoA belong to the Rho family of GTPases, small monomeric G proteins | Apis mellifera |
3.6.5.2 | physiological function | Rac and RhoA belong to the small, monomeric G proteins of the Rho family of GTPases, that, when activated, initiate a signaling cascade that reorganizes the neuronal cytoskeleton. Rho GTPases regulate cellular morphogenesis through direct interactions with actin and microtubule-organizing proteins. Rho GTPases are cycling between the inactive GDP-bound and the active GTP-bound forms is controlled by guanine nucleotide exchange factors, GTPase activating proteins, and guanine nucleotide dissociation inhibitors | Apis mellifera |