EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.83 | Bacillus anthracis | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.24.83 | anthrax lethal factor | - |
Bacillus anthracis |
3.4.24.83 | anthrax lethal toxin | - |
Bacillus anthracis |
3.4.24.83 | LeTx | - |
Bacillus anthracis |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.4.24.83 | physiological function | anthrax lethal toxin is a virulence factor of Bacilillus anthracis that is a bivalent toxin, containing lethal factor and protective Ag proteins, which causes cytotoxicity and altered macrophage function. Anthrax lethal toxin exposure results in early K+ efflux from macrophages associated with caspase-1 activation and increased interleukin-1beta release | Bacillus anthracis |