EC Number | Application | Comment | Organism |
---|---|---|---|
2.3.1.122 | drug development | antigen 85 proteins are potential drug targets | Mycobacterium tuberculosis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.122 | ethyl 3-phenoxybenzyl butylphosphonate | - |
Mycobacterium tuberculosis | |
2.3.1.122 | additional information | inhibitor screening by molecular docking, overview | Mycobacterium tuberculosis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.122 | 2 alpha,alpha-trehalose 6-mycolate | Mycobacterium tuberculosis | - |
alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.122 | Mycobacterium tuberculosis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.122 | 2 alpha,alpha-trehalose 6-mycolate | - |
Mycobacterium tuberculosis | alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.122 | antigen 85C | - |
Mycobacterium tuberculosis |
2.3.1.122 | mycolyltransferase | - |
Mycobacterium tuberculosis |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.3.1.122 | 0.002 | - |
pH and temperature not specified in the publication | Mycobacterium tuberculosis | ethyl 3-phenoxybenzyl butylphosphonate |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.3.1.122 | physiological function | the enzyme is responsible for converting trehalose monomycolate to trehalose dimycolate, which contributes to cell wall stability | Mycobacterium tuberculosis |