Literature summary extracted from

Tsai, C.; Henderson, L.
Degradation of O phosphohydroxylysine by rat liver. Purification of the phospho lyase (1974), J. Biol. Chem., 249, 5784-5789.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.2.3.134	Borohydride	inhibits the holoenzyme but no effect on the apoenzyme	Rattus norvegicus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
4.2.3.134	0.0036	-	(5R)-5-phosphohydroxy-L-lysine	pH 7.4, 37°C	Rattus norvegicus
4.2.3.134	0.0105	-	(5R)-5-phosphohydroxy-L-lysine	pH 7.4, 37°C	Rattus norvegicus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
4.2.3.134	140000	-	gel filtration	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.3.134	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
4.2.3.134	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.3.134	(5R)-5-phosphohydroxy-L-lysine + H2O	-	Rattus norvegicus	(S)-2-amino-6-oxohexanoate + NH3 + phosphate	-	?
4.2.3.134	phosphoallohydroxy-L-lysine + H2O	-	Rattus norvegicus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.2.3.134	phospho lyase	-	Rattus norvegicus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
4.2.3.134	pyridoxal 5'-phosphate	-	Rattus norvegicus

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Release 2023.1 (January 2023)