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Literature summary extracted from

  • Huang, J.; Xin, Y.; Zhang, W.
    Isolation, characterization and identification of a Paracoccus sp. 2-haloacid-degrading bacterium from the marine sponge Hymeniacidon perlevis (2011), J. Basic Microbiol., 51, 318-324.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.8.1.2 gene dehII, DNA and amino acid sequence determination and analysis Hymeniacidon perlevis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.8.1.2 (S)-2-bromopropionic acid + H2O Hymeniacidon perlevis
-
 (R)-2-hydroxypropionic acid + bromide
-
 ?
3.8.1.2 (S)-2-chloropropionic acid + H2O Hymeniacidon perlevis
-
 (R)-2-hydroxypropionic acid + chloride
-
 ?
3.8.1.2 iodoacetic acid + H2O Hymeniacidon perlevis
-
 acetic acid + iodide + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.8.1.2 Hymeniacidon perlevis
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.8.1.2 0.06
-
 substrate (S)-2-chloropropionic acid, pH 7.3, 30°C Hymeniacidon perlevis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.8.1.2 (S)-2-bromopropionic acid + H2O
-
 Hymeniacidon perlevis (R)-2-hydroxypropionic acid + bromide
-
 ?
3.8.1.2 (S)-2-chloropropionic acid + H2O
-
 Hymeniacidon perlevis (R)-2-hydroxypropionic acid + chloride
-
 ?
3.8.1.2 (S)-2-chloropropionic acid + H2O high activity Hymeniacidon perlevis (R)-2-hydroxypropionic acid + chloride
-
 ?
3.8.1.2 iodoacetic acid + H2O
-
 Hymeniacidon perlevis acetic acid + iodide + H+
-
 ?
3.8.1.2 iodoacetic acid + H2O best substrate Hymeniacidon perlevis acetic acid + iodide + H+
-
 ?
3.8.1.2 additional information no activity with 2-fluoropropionic acid Hymeniacidon perlevis ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.8.1.2 DEH99
-
 Hymeniacidon perlevis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.8.1.2 30
-
 assay at Hymeniacidon perlevis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.8.1.2 7.3
-
 assay at Hymeniacidon perlevis

General Information

EC Number General Information Comment Organism
3.8.1.2 evolution the enzyme belongs to the Group II family Hymeniacidon perlevis
3.8.1.2 physiological function DEH99 is a (S)-2-haloacid dehalogenase, which can degrade (S)-2-chloropropionic acid, (S)-2-bromopropionic acid, and iodoacetic acid Hymeniacidon perlevis