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Literature summary extracted from

  • Zhu, B.T.; Wu, K.Y.; Wang, P.; Cai, M.X.; Conney, A.H.
    O-methylation of catechol estrogens by human placental catechol-o-methyltransferase: interindividual differences in sensitivity to heat inactivation and to inhibition by dietary polyphenols (2010), Drug Metab. Dispos., 38, 1892-1899.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.6 (-)-epigallocatechin-3-gallate
-
 Homo sapiens
2.1.1.6 quercetin
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.6 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.6 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.6 2-hydroxyestradiol + S-adenosyl-L-methionine
-
 Homo sapiens 2-hydroxyestradiol 3-methyl ether + S-adenosyl-L-homocysteine
-
 ?
2.1.1.6 2-hydroxyestradiol + S-adenosyl-L-methionine
-
 Homo sapiens 2-methoxyestradiol + S-adenosyl-L-homocysteine
-
 ?
2.1.1.6 4-hydroxyestradiol + S-adenosyl-L-methionine
-
 Homo sapiens ? + S-adenosyl-L-homocysteine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.6 catechol-O-methyltransferase
-
 Homo sapiens