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Literature summary extracted from

  • Palanivelu, R.; Brass, L.; Edlund, A.; Preuss, D.
    Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels (2003), Cell, 114, 47-59.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.6.1.96 genes pop2-1, pop2-2, and pop2-3, pop2-1 are located on chromosome 3, DNA and amino acid sequennce determination and analysis Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
2.6.1.96 additional information construction of pop2-1 mutant, phenotype, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.96 4-aminobutanoate + pyruvate Arabidopsis thaliana
-
 succinate semialdehyde + L-alanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.96 Arabidopsis thaliana Q94CE5 POP2; gene pop2-1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.96 flower
-
 Arabidopsis thaliana
-
2.6.1.96 fruit
-
 Arabidopsis thaliana
-
2.6.1.96 integument
-
 Arabidopsis thaliana
-
2.6.1.96 leaf
-
 Arabidopsis thaliana
-
2.6.1.96 pistil
-
 Arabidopsis thaliana
-
2.6.1.96 plant funiculus
-
 Arabidopsis thaliana
-
2.6.1.96 plant ovary wall
-
 Arabidopsis thaliana
-
2.6.1.96 plant ovule
-
 Arabidopsis thaliana
-
2.6.1.96 plant septum
-
 Arabidopsis thaliana
-
2.6.1.96 pollen
-
 Arabidopsis thaliana
-
2.6.1.96 pollen tube
-
 Arabidopsis thaliana
-
2.6.1.96 stigma
-
 Arabidopsis thaliana
-
2.6.1.96 style
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.96 4-aminobutanoate + pyruvate
-
 Arabidopsis thaliana succinate semialdehyde + L-alanine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.6.1.96 GABA transaminase
-
 Arabidopsis thaliana
2.6.1.96 Pop2
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.96 pyridoxal 5'-phosphate
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.6.1.96 malfunction enzyme-deficient pop2 flowers accumulate GABA, and the growth of many pop2 pollen tubes is arrested, consistent with their in vitro GABA hypersensitivity. Some pop2 tubes continue to grow toward ovules, yet they are misguided, presumably because they target ectopic GABA on the ovule surface. Wild-type tubes decreased POP2 activity leads to increased levels of GABA throughout the ovule, coupled with aberrant growth and guidance of pop2 pollen tubes Arabidopsis thaliana
2.6.1.96 physiological function the POP2 gene encodes a transaminase that degrades GABA and contributes to the formation of a gradient leading up to the micropyle, effect of GABA on pollen tube elongation in vitro Arabidopsis thaliana