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Literature summary extracted from

  • Boros, S.; Xi, Q.; Dimke, H.; van der Kemp, A.W.; Tudpor, K.; Verkaart, S.; Lee, K.P.; Bindels, R.J.; Hoenderop, J.G.
    Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner (2012), Cell. Mol. Life Sci., 69, 981-992.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 cadaverine complete inhibition at 0.15 mM Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ dependent on Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.13 75000
-
 x * 75000, SDS-PAGE Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 connecting tubule the enzyme is secreted into the apical medium of polarized cultures of rabbit connecting tubule and cortical collecting duct cells Mus musculus
-
2.3.2.13 cortical collecting duct cell the enzyme is detected in the apical medium of polarized cultures of rabbit connecting tubule and cortical collecting duct cells Mus musculus
-
2.3.2.13 urine the enzyme is secreted into the pro-urine Mus musculus
-

Subunits

EC Number Subunits Comment Organism
2.3.2.13 ? x * 75000, SDS-PAGE Mus musculus

Synonyms

EC Number Synonyms Comment Organism
2.3.2.13 tissue transglutaminase
-
 Mus musculus
2.3.2.13 tTG
-
 Mus musculus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.3.2.13 95
-
 the enzyme is inactive after 10 min at 95°C Mus musculus

General Information

EC Number General Information Comment Organism
2.3.2.13 physiological function the enzyme reduces the pore diameter and inhibits the activity of transient receptor potential vanilloid 5 in an N-glycosylation-dependent manner Mus musculus