EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.180 | His-tagged protein expressed in Escherichia coli BL21(DE3) | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.180 | 2-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-5-(2-methylbenzyl)-1,3,4-oxadiazole | - |
Escherichia coli | |
2.3.1.180 | 2-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol | - |
Escherichia coli | |
2.3.1.180 | 2-(2-methoxyphenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | - |
Escherichia coli | |
2.3.1.180 | 2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | - |
Escherichia coli | |
2.3.1.180 | 2-(3-methoxyphenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | - |
Escherichia coli | |
2.3.1.180 | 2-(4-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | - |
Escherichia coli | |
2.3.1.180 | 2-(4-chlorophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | - |
Escherichia coli | |
2.3.1.180 | 2-(4-fluorophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | - |
Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.180 | Escherichia coli | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.180 | immobilized metal ion affinity chromatography (Ni2+) | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.180 | malonyl-ACP + acetyl-CoA | - |
Escherichia coli | CO2 + CoA + acetoacetyl-ACP | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.180 | beta-ketoacyl-acyl carrier protein synthase III | - |
Escherichia coli |
2.3.1.180 | FabH | - |
Escherichia coli |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.3.1.180 | 0.0043 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-(2-methoxyphenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | |
2.3.1.180 | 0.0051 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-5-(2-methylbenzyl)-1,3,4-oxadiazole | |
2.3.1.180 | 0.0094 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-(3-methoxyphenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | |
2.3.1.180 | 0.0169 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | |
2.3.1.180 | 0.0186 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-(4-fluorophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | |
2.3.1.180 | 0.0283 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-(4-chlorophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole | |
2.3.1.180 | 0.0405 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol | |
2.3.1.180 | 0.0438 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 2-(4-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole |