EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.180 | overexpressed in E. coli DH10B cells using the pET30 vector, selenomethionine-substituted protein expressed in Escherichia coli BL21(DE3) | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.180 | (E)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-bromophenylamino)acrylate | - |
Escherichia coli | |
2.3.1.180 | (E)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-isopropylphenylamino)acrylate | - |
Escherichia coli | |
2.3.1.180 | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(2,4-dibromophenylamino)acrylate | - |
Escherichia coli | |
2.3.1.180 | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(2-chlorophenylamino)acrylate | - |
Escherichia coli | |
2.3.1.180 | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-bromophenylamino)acrylate | - |
Escherichia coli | |
2.3.1.180 | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-fluorophenylamino)acrylate | - |
Escherichia coli | |
2.3.1.180 | (Z)-ethyl 3-(p-toluidino)-2-(4-(benzyloxy)phenyl)acrylate | - |
Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.180 | Escherichia coli | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.180 | to homogeneity in three chromatographic steps (Q-Sepharose, MonoQ, and hydroxyapatite), immobilized metal ion affinity chromatography (Ni2+) | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.180 | malonyl-ACP + acetyl-CoA | - |
Escherichia coli | CO2 + CoA + acetoacetyl-ACP | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.180 | beta-ketoacyl-acyl carrier protein synthase III | - |
Escherichia coli |
2.3.1.180 | FabH | - |
Escherichia coli |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.3.1.180 | 0.0026 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | (Z)-ethyl 3-(p-toluidino)-2-(4-(benzyloxy)phenyl)acrylate | |
2.3.1.180 | 0.0033 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-bromophenylamino)acrylate | |
2.3.1.180 | 0.0082 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-fluorophenylamino)acrylate | |
2.3.1.180 | 0.0085 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | (E)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-isopropylphenylamino)acrylate | |
2.3.1.180 | 0.024 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(2,4-dibromophenylamino)acrylate | |
2.3.1.180 | 0.028 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | (Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(2-chlorophenylamino)acrylate | |
2.3.1.180 | 0.043 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | (E)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-bromophenylamino)acrylate |