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Literature summary extracted from
- Lysostaphin-functionalized cellulose fibers with antistaphylococcal activity for wound healing applications (2011), Biomaterials, 32, 9557-9567.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.24.75 | medicine | lysostaphin-functionalized cellulose fibers show activity against Staphylococcus aureus in an in vitro skin model (HaCaT keratinocyte) with low toxicity toward keratinocytes, suggesting good biocompatibility for these materials as antimicrobial matrices in wound healing applications | Staphylococcus simulans |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.75 | Peptidoglycan + H2O | Staphylococcus simulans | the enzyme is highly specific and effective against Staphylococcus aureus cleaving the pentaglycine cross-bridges in the peptidoglycan layer of staphylococcal cell walls | Fragments of peptidoglycan | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.75 | Staphylococcus simulans | P10547 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.75 | Peptidoglycan + H2O | the enzyme is highly specific and effective against Staphylococcus aureus cleaving the pentaglycine cross-bridges in the peptidoglycan layer of staphylococcal cell walls | Staphylococcus simulans | Fragments of peptidoglycan | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.75 | Lst | - |
Staphylococcus simulans |
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Release 2023.1 (January 2023)
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