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Literature summary extracted from

  • Zhao, S.; Ragsdale, S.
    A conformational change in the methyltransferase from Clostridium thermoaceticum facilitates the methyl transfer from (6S)-methyltetrahydrofolate to the corrinoid/iron-sulfur protein in the acetyl-CoA pathway (1996), Biochemistry, 35, 2476-2481.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.258 4,4'-bis(1-(phenylamino)-8-naphthalenesulfonate)
-
Moorella thermoacetica

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.258 Moorella thermoacetica
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.258
-
Moorella thermoacetica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.258 additional information only the protonated enzyme form is active Moorella thermoacetica ?
-
?
2.1.1.258 [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate
-
Moorella thermoacetica [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate
-
?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.258 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase
-
Moorella thermoacetica
2.1.1.258 MeTr
-
Moorella thermoacetica

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.1.258 Cobalamin dependent on Moorella thermoacetica

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.1.1.258 0.026
-
4,4'-bis(1-(phenylamino)-8-naphthalenesulfonate) at pH 5.8 and 25°C Moorella thermoacetica