EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
7.2.2.3 | additional information | the addition of 0.001 mM guanosine 5-O-(2-thiodiphosphate) does not change the enzyme activity | Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
7.2.2.3 | Furosemide | - |
Sus scrofa | |
7.2.2.3 | prostaglandin E2 | dose-dependent inhibition with maximal effect at 1 nM. The addition of 0.001 mM prostaglandin E2 decreases Na+-ATPase activity by 41%. The inhibitory effect of prostaglandin E2 on proximal tubule Na+-ATPase activity involves G protein and the activation of protein kinase A. The protein A-mediated inhibitory effect of prostaglandin E2 on Na+-ATPase activity requires previous activation of protein kinase C | Sus scrofa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
7.2.2.3 | membrane | - |
Sus scrofa | 16020 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.2.2.3 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
7.2.2.3 | renal proximal tubule | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.2.3 | ATP + H2O + Na+/in | - |
Sus scrofa | ADP + phosphate + Na+/out | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.2.2.3 | Na+-ATPase | - |
Sus scrofa |