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Literature summary extracted from

  • Lin, X.; Liang, X.; Tang, J.; Chen, J.; Qiu, P.; Yan, G.
    The effect of the fibrinolytic enzyme FIIa from Agkistrodon acutus venom on acute pulmonary thromboembolism (2011), Acta Pharmacol. Sin., 32, 239-244.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
3.4.24.72 medicine the enzyme effectively protects against acute pulmonary thromboembolism via degradation of thrombi with less activation of plasminogen Deinagkistrodon acutus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.72 Zn2+ essential for hydrolytic activity Deinagkistrodon acutus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.72 Fibrin + H2O Deinagkistrodon acutus the enzyme has the ability to directly degrade fibrin in vitro and effectively dissolve thrombi in vivo without activating plasminogen or influencing the activities of tissue plasminogen activator and plasminogen activator inhibitor-1 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.72 Deinagkistrodon acutus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.72 venom
-
 Deinagkistrodon acutus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.72 Fibrin + H2O the enzyme has the ability to directly degrade fibrin in vitro and effectively dissolve thrombi in vivo without activating plasminogen or influencing the activities of tissue plasminogen activator and plasminogen activator inhibitor-1 Deinagkistrodon acutus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.72 FIIa
-
 Deinagkistrodon acutus