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Literature summary extracted from

  • Xu, M.; Wilderman, P.; Peters, R.
    Following evolutions lead to a single residue switch for diterpene synthase product outcome (2007), Proc. Natl. Acad. Sci. USA, 104, 7387-7401.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
4.2.3.103 I664T the mutant specifically produces pimara-8(14),15-diene from ent-copalyl diphosphate Oryza sativa Japonica Group
4.2.3.103 I664T the mutant specifically produces pimara-8(14),15-diene from ent-copalyl diphosphate Oryza sativa Indica Group
4.2.3.103 I718V the mutant specifically produces ent-isokaur-15-ene from ent-copalyl diphosphate Oryza sativa Indica Group
4.2.3.103 V661L the mutant specifically produces ent-isokaur-15-ene from ent-copalyl diphosphate Oryza sativa Indica Group

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.103 Oryza sativa Indica Group A4KAG7 isofom KSL5i
-
4.2.3.103 Oryza sativa Japonica Group A4KAG8 isofom KSL6
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.103 ent-copalyl diphosphate
-
 Oryza sativa Japonica Group ent-isokaurene + diphosphate
-
 ?
4.2.3.103 ent-copalyl diphosphate more than 90% yield Oryza sativa Indica Group ent-isokaurene + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.103 KSL5i
-
 Oryza sativa Indica Group
4.2.3.103 KSL6
-
 Oryza sativa Japonica Group