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Literature summary extracted from
- Studies on collagen-tannic acid-collagenase ternary system: Inhibition of collagenase against collagenolytic degradation of extracellular matrix component of collagen (2011), J. Enzyme Inhib. Med. Chem., 27, 451-457.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.3 | Tannic acid | competitive, almost complete inhibition. Pretreatment of collagen fibers with tannic acid results in polymerization and complex formation | Hathewaya histolytica |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.24.3 | 0.555 | - |
N-[3-(2-furyl) acryloyl]-L-Leu-Gly-L-Pro-L-Ala | pH 7.5, 25°C | Hathewaya histolytica | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.3 | Hathewaya histolytica | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.3 | N-[3-(2-furyl) acryloyl]-L-Leu-Gly-L-Pro-L-Ala + H2O | - |
Hathewaya histolytica | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.3 | ChC | - |
Hathewaya histolytica |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.24.3 | 0.02 | - |
Tannic acid | pH 7.5, 25°C | Hathewaya histolytica | |
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Release 2023.1 (January 2023)
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