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Literature summary extracted from

  • Teoh, K.H.; Polichuk, D.R.; Reed, D.W.; Nowak, G.; Covello, P.S.
    Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin (2006), FEBS Lett., 580, 1411-1416.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.114 expression in Saccharomyces cerevisiae Artemisia annua

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.114 Artemisia annua Q1PS23
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.114 flower bud moderate expression Artemisia annua
-
1.14.14.114 leaf low expression Artemisia annua
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1.14.14.114 root low expression Artemisia annua
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1.14.14.114 trichome highest expression Artemisia annua
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.114 amorpha-4,11-diene + [reduced NADPH-hemoprotein reductase] + O2
-
 Artemisia annua artemisinic alcohol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.114 artemisinic alcohol + [reduced NADPH-hemoprotein reductase] + O2
-
 Artemisia annua artemisinic aldehyde + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.114 artemisinic aldehyde + [reduced NADPH-hemoprotein reductase] + O2
-
 Artemisia annua artemisinate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.114 additional information no substrates: limonene, alpha-pinene, beta-pinene and pinocarveol, and the sesquiterpenes ()-alloisolongifolene, caryophyllene, ()-alpha-gurjunene, (+)-gamma-gurjunene, (+)-ledene,(+)-beta-selinene and (+)-valencene Artemisia annua ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.114 amorpha-4,11-diene C-12 oxidase
-
 Artemisia annua
1.14.14.114 CYP71AV1
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 Artemisia annua