EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.37 | kappa-casein | inhibits proteolytic activity associated with Porphyromonas gingivalis whole cells, purified RgpA-Kgp proteinase-adhesin complexes, and purified RgpB proteinase. The peptide kappa-casein(109-137) exhibits synergism with Zn(II) against both Arg- and Lys-specific proteinases. Active region for inhibition is identified as kappa-casein (117-137). Kappa-casein inhibits in an uncompetitive manner | Porphyromonas gingivalis | |
3.4.22.47 | kappa-casein | inhibits proteolytic activity associated with Porphyromonas gingivalis whole cells, purified RgpA-Kgp proteinase-adhesin complexes, and purified RgpB proteinase. The peptide kappa-casein(109-137) exhibits synergism with Zn(II) against both Arg- and Lys-specific proteinases. Active region for inhibition is identified as kappa-casein (117-137). Kappa-casein inhibits in an uncompetitive manner | Porphyromonas gingivalis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.37 | Porphyromonas gingivalis | - |
- |
- |
3.4.22.47 | Porphyromonas gingivalis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.37 | Nalpha-benzoyl-L-Arg-4-nitroanilide + H2O | - |
Porphyromonas gingivalis | Nalpha-benzoyl-L-Arg + 4-nitroaniline | - |
? | |
3.4.22.47 | N-(p-tosyl)-Gly-Pro-Lys 4-nitroanilide + H2O | - |
Porphyromonas gingivalis | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.37 | RgpA | - |
Porphyromonas gingivalis |
3.4.22.37 | RgpB | - |
Porphyromonas gingivalis |
3.4.22.47 | KGP | - |
Porphyromonas gingivalis |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.22.37 | 37 | - |
assay at | Porphyromonas gingivalis |
3.4.22.47 | 37 | - |
assay at | Porphyromonas gingivalis |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.22.37 | 8 | - |
assay at | Porphyromonas gingivalis |
3.4.22.47 | 8 | - |
assay at | Porphyromonas gingivalis |