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Literature summary extracted from

  • Pietkiewicz, J.; Bronowicka-Szyde?ko, A.; Dzierzba, K.; Danielewicz, R.; Gamian, A.
    Glycation of the muscle-specific enolase by reactive carbonyls: effect of temperature and the protection role of carnosine, pyridoxamine and phosphatidylserine (2011), Protein J., 30, 149-158.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.11 4-hydroxy-2-nonenal
-
 Homo sapiens
4.2.1.11 4-hydroxy-2-nonenal
-
 Sus scrofa
4.2.1.11 acrolein
-
 Homo sapiens
4.2.1.11 acrolein
-
 Sus scrofa
4.2.1.11 methylglyoxal
-
 Homo sapiens
4.2.1.11 methylglyoxal
-
 Sus scrofa
4.2.1.11 additional information the muscle-specific enolase is used as a model enzyme for inhibition analysis by acrolein, 4-hydroxy-2-nonenal, and trans-2-nonenal, incubation for 1-24 h at 25°C, 37°C, and 45°C, overview. The compounds show inhibition effectivity in the following descending order: inhibition degree of enolase activity occurred in following order: 4-hydroxy-2-nonenal, acrolein, methylglyoxal, trans-2-nonenal, overview Homo sapiens
4.2.1.11 additional information the muscle-specific enolase is used as a model enzyme for inhibition analysis by acrolein, 4-hydroxy-2-nonenal, and trans-2-nonenal, incubation for 1-24 h at 25°C, 37°C, and 45°C, overview. The compounds show inhibition effectivity in the following descending order: inhibition degree of enolase activity occurred in following order: 4-hydroxy-2-nonenal, acrolein, methylglyoxal, trans-2-nonenal, overview Sus scrofa
4.2.1.11 trans-2-nonenal
-
 Homo sapiens
4.2.1.11 trans-2-nonenal
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.11 Homo sapiens
-
-
-
4.2.1.11 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.11 native enzyme from muscle by ammonium sulfate fractionation and ion exchange chromatography Homo sapiens
4.2.1.11 native enzyme from muscle by ammonium sulfate fractionation and ion exchange chromatography Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.11 skeletal muscle muscle-specific enolase Homo sapiens
-
4.2.1.11 skeletal muscle muscle-specific enolase Sus scrofa
-

Synonyms

EC Number Synonyms Comment Organism
4.2.1.11 beta-enolase
-
 Homo sapiens
4.2.1.11 beta-enolase
-
 Sus scrofa
4.2.1.11 enolase
-
 Homo sapiens
4.2.1.11 enolase
-
 Sus scrofa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.2.1.11 22
-
 assay at room temperature Homo sapiens
4.2.1.11 22
-
 assay at room temperature Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.1.11 6.8
-
 assay at Homo sapiens
4.2.1.11 6.8
-
 assay at Sus scrofa

General Information

EC Number General Information Comment Organism
4.2.1.11 additional information the human muscle-specific enolase is less susceptible to inactivation by reactive aldehydes than the pig enzyme Homo sapiens
4.2.1.11 additional information the human muscle-specific enolase is less susceptible to inactivation by reactive aldehydes than the pig enzyme Sus scrofa