EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | Prostaglandin H2 | Mus musculus | - |
Prostaglandin E2 | - |
? | |
5.3.99.3 | Prostaglandin H2 | Rattus norvegicus | - |
Prostaglandin E2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.3 | Mus musculus | - |
- |
- |
5.3.99.3 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
5.3.99.3 | 3Y1 cell | - |
Rattus norvegicus | - |
5.3.99.3 | embryonic fibroblast | - |
Mus musculus | - |
5.3.99.3 | MEF cell | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | Prostaglandin H2 | - |
Mus musculus | Prostaglandin E2 | - |
? | |
5.3.99.3 | Prostaglandin H2 | - |
Rattus norvegicus | Prostaglandin E2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.3 | CPGES | - |
Mus musculus |
5.3.99.3 | CPGES | - |
Rattus norvegicus |
5.3.99.3 | p23 | - |
Mus musculus |
5.3.99.3 | p23 | - |
Rattus norvegicus |
5.3.99.3 | Prostaglandin E synthase | - |
Mus musculus |
5.3.99.3 | Prostaglandin E synthase | - |
Rattus norvegicus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
5.3.99.3 | malfunction | embryonic fibroblasts deficient in cPGES/p23 decrease the expression of the prostaglandin E2 degrading enzyme, 15-hydroxyprostaglandin dehydrogenase, which catalyzes the inactivating conversion of the PGE2 15-OH to a 15-keto group | Mus musculus |
5.3.99.3 | malfunction | fibroblasts deficient in cPGES/p23 decrease the expression of the prostaglandin E2 degrading enzyme, 15-hydroxyprostaglandin dehydrogenase, which catalyzes the inactivating conversion of the PGE2 15-OH to a 15-keto group | Rattus norvegicus |
5.3.99.3 | metabolism | the prostaglandin E2-inactivating pathway is controlled by cPGES/p23 | Mus musculus |
5.3.99.3 | metabolism | the prostaglandin E2-inactivating pathway is controlled by cPGES/p23 | Rattus norvegicus |