EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.4.1.2 | Avidin | general inhibitor of ACCase activity | Arabidopsis thaliana | |
6.4.1.2 | fenoxaprop | a specific inhibitor of the cytosolic ACCase, does not affect the activity of chloroplast ACCase | Arabidopsis thaliana | |
6.4.1.2 | PII protein | recombinant Arabidopsis PII protein inhibits chloroplastic ACCase activity dose-dependently and noncompetitively via binding to its BCCP subunit, and this is completely reversed in the presence of 2-oxoglutarate, pyruvate, or oxaloacetate. PII protein decreases the Vmax of the ACCase reaction without altering the Km for acetyl-CoA | Arabidopsis thaliana |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
6.4.1.2 | chloroplast | - |
Arabidopsis thaliana | 9507 | - |
6.4.1.2 | cytosol | - |
Arabidopsis thaliana | 5829 | - |
6.4.1.2 | plastid | - |
Arabidopsis thaliana | 9536 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.4.1.2 | Arabidopsis thaliana | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.4.1.2 | leaf | - |
Arabidopsis thaliana | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.4.1.2 | ATP + acetyl-CoA + HCO3- | - |
Arabidopsis thaliana | ADP + malonyl-CoA + phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.4.1.2 | ACCase | - |
Arabidopsis thaliana |
6.4.1.2 | BCCP1 | ACCase subunit | Arabidopsis thaliana |
6.4.1.2 | BCCP2 | ACCase subunit | Arabidopsis thaliana |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.4.1.2 | ATP | - |
Arabidopsis thaliana | |
6.4.1.2 | biotin | - |
Arabidopsis thaliana |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
6.4.1.2 | 0.00015 | - |
apparent value, in 100 mM Tricine (pH 8.2), at 30°C | Arabidopsis thaliana | PII protein |
EC Number | General Information | Comment | Organism |
---|---|---|---|
6.4.1.2 | physiological function | ACCase is a key enzyme initiating the synthesis of fatty acids in plastids | Arabidopsis thaliana |