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Literature summary extracted from

  • Setoyama, D.; Ito, R.; Takagi, Y.; Sekiguchi, M.
    Molecular actions of Escherichia coli MutT for control of spontaneous mutagenesis (2010), Mutat. Res., 707, 9-14.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.55 8-oxo-dGTP + H2O Escherichia coli MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure 8-oxo-dGMP + diphosphate
-
 ?
3.6.1.55 8-oxo-dGTP + H2O Escherichia coli CC101 MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure 8-oxo-dGMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.55 Escherichia coli
-
-
-
3.6.1.55 Escherichia coli CC101
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.55 8-oxo-dGTP + H2O
-
 Escherichia coli 8-oxo-dGMP + diphosphate
-
 ?
3.6.1.55 8-oxo-dGTP + H2O MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure Escherichia coli 8-oxo-dGMP + diphosphate
-
 ?
3.6.1.55 8-oxo-dGTP + H2O
-
 Escherichia coli CC101 8-oxo-dGMP + diphosphate
-
 ?
3.6.1.55 8-oxo-dGTP + H2O MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure Escherichia coli CC101 8-oxo-dGMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.55 MutT
-
 Escherichia coli

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.6.1.55 37
-
 assay at Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.55 8
-
 assay at Escherichia coli

Expression

EC Number Organism Comment Expression
3.6.1.55 Escherichia coli MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure additional information

General Information

EC Number General Information Comment Organism
3.6.1.55 physiological function MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure Escherichia coli