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Literature summary extracted from

  • Reyes-Carmona, S.; Valadez-Graham, V.; Aguilar-Fuentes, J.; Zurita, M.; Leon-Del-Rio, A.
    Trafficking and chromatin dynamics of holocarboxylase synthetase during development of Drosophila melanogaster (2011), Mol. Genet. Metab., 103, 240-248.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.4.10 expression in Escherichia coli Drosophila melanogaster

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.3.4.10 nucleus HCS migrates to the nucleus at the gastrulation stage. In polytene chromosomes, it is associated to heterochromatin bands where it co-localizes with histone 3 trimethylated at lysine 9 but not with the euchromatin mark histone 3 acetylated at lysine 9. HCS associates with the hsp70 promoter. On heat-shock activation of the hsp70 promoter, HCS is displaced and the promoter region becomes enriched with the TFIIH subunits XPD and XPB and elongating RNA pol I Drosophila melanogaster 5634
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Organism

EC Number Organism UniProt Comment Textmining
6.3.4.10 Drosophila melanogaster
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.4.10 embryo
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 Drosophila melanogaster
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6.3.4.10 salivary gland
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 Drosophila melanogaster
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General Information

EC Number General Information Comment Organism
6.3.4.10 physiological function HCS migrates to the nucleus at the gastrulation stage. In polytene chromosomes, it is associated to heterochromatin bands where it co-localizes with histone 3 trimethylated at lysine 9 but not with the euchromatin mark histone 3 acetylated at lysine 9. HCS associates with the hsp70 promoter. On heat-shock activation of the hsp70 promoter, HCS is displaced and the promoter region becomes enriched with the TFIIH subunits XPD and XPB and elongating RNA pol I Drosophila melanogaster