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Literature summary extracted from
- Transgenic tobacco plant expressing environmental E. coli merA gene for enhanced volatilization of ionic mercury (2010), J. Microbiol. Biotechnol., 20, 917-924.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.16.1.1 | gene merA, recombinant expression in transgenoc Nicotiana tabacum cv. Xanthium plants using gene transfer by Agrobacterium tumefaciens. Transgenic tobacco expressing merA volatilizes significantly more mercury than wild-type plants. Subcloning in Escherichia coli strains DH5alpha and BL21(DE3) | Escherichia coli |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.16.1.1 | Hg + NADP+ + H+ | Escherichia coli | MerA catalyzes the bioconversion of toxic Hg2+ to the least toxic elemental Hg0, and is capable of reducing the Hg2+, via NADPH as an electron donor | Hg2+ + NADPH | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.16.1.1 | Escherichia coli | Q93UN8 | plasmid R100; Escherichia coli containing plasmid R100 encoding gene merA | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.16.1.1 | Hg + NADP+ + H+ | - |
Escherichia coli | Hg2+ + NADPH | - |
? | |
| 1.16.1.1 | Hg + NADP+ + H+ | MerA catalyzes the bioconversion of toxic Hg2+ to the least toxic elemental Hg0, and is capable of reducing the Hg2+, via NADPH as an electron donor | Escherichia coli | Hg2+ + NADPH | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.16.1.1 | MerA | - |
Escherichia coli |
| 1.16.1.1 | mercuric reductase | - |
Escherichia coli |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.16.1.1 | NADPH | - |
Escherichia coli | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.16.1.1 | physiological function | MerA catalyzes the bioconversion of toxic Hg2+ to the least toxic elemental Hg0 | Escherichia coli |
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Release 2023.1 (January 2023)
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