Any feedback?
Literature summary extracted from
- The juvenile hormone (JH) epoxide hydrolase gene in the honey bee (Apis mellifera) genome encodes a protein which has negligible participation in JH degradation (2010), J. Insect Physiol., 56, 1139-1146.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.59 | 3-octylthio-1,1,1-trifluoro-2-propanone | specific inhibitor, 95-100% inhibition at 2 mM in hemolymph and fat body | Apis mellifera |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.59 | juvenile hormone III + H2O | Apis mellifera | JH esterase hydrolyzes the methyl ester to produce juvenile hormone acid | juvenile hormone III acid + methanol | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.59 | Apis mellifera | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.59 | fat body | - |
Apis mellifera | - |
| 3.1.1.59 | hemolymph | - |
Apis mellifera | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.59 | juvenile hormone III + H2O | - |
Apis mellifera | juvenile hormone III acid + methanol | - |
? | |
| 3.1.1.59 | juvenile hormone III + H2O | JH esterase hydrolyzes the methyl ester to produce juvenile hormone acid | Apis mellifera | juvenile hormone III acid + methanol | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.1.59 | JH esterase | - |
Apis mellifera |
| 3.1.1.59 | JHE | - |
Apis mellifera |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.59 | 30 | - |
assay at | Apis mellifera |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.59 | 7.4 | - |
assay at | Apis mellifera |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.1.1.59 | physiological function | JHE is the enzyme primarily performing juvenile hormone degradation in Apis mellifera, while the JH epoxide hydrolase, EC 3.3.2.9, plays a negligible role | Apis mellifera |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
