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Literature summary extracted from

  • Kocourkova, D.; Krckova, Z.; Pejchar, P.; Veselkova, S.; Valentova, O.; Wimalasekera, R.; Scherer, G.F.; Martinec, J.
    The phosphatidylcholine-hydrolysing phospholipase C NPC4 plays a role in response of Arabidopsis roots to salt stress (2011), J. Exp. Bot., 62, 3753-3763.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.3 phosphatidylcholine + H2O Arabidopsis thaliana
-
 1,2-diacyl-sn-glycerol + choline phosphate
-
 ?
3.1.4.3 phosphatidylcholine + H2O Arabidopsis thaliana Col-0
-
 1,2-diacyl-sn-glycerol + choline phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.3 Arabidopsis thaliana Q9SRQ7 NPC4; gene NPC4
-
3.1.4.3 Arabidopsis thaliana Col-0 Q9SRQ7 NPC4; gene NPC4
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.3 root
-
 Arabidopsis thaliana
-
3.1.4.3 root tip
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.3 phosphatidylcholine + H2O
-
 Arabidopsis thaliana 1,2-diacyl-sn-glycerol + choline phosphate
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Arabidopsis thaliana Col-0 1,2-diacyl-sn-glycerol + choline phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.3 More the enzyme is a member of the plant phospholipase family Arabidopsis thaliana
3.1.4.3 non-specific phospholipase C
-
 Arabidopsis thaliana
3.1.4.3 NPC
-
 Arabidopsis thaliana
3.1.4.3 phosphatidylcholine-hydrolysing phospholipase C
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
3.1.4.3 Arabidopsis thaliana expression of gene NPC4 in root tips is highly induced by NaCl, maximum expression from 3 h to 6 h after the salt treatment dependent on salt concentration up

General Information

EC Number General Information Comment Organism
3.1.4.3 malfunction NPC4 knockout plants show increased sensitivity to salinity as compared with wild-type plants. Under salt stress npc4 plants have shorter roots, lower fresh weight, and reduced seed germination Arabidopsis thaliana
3.1.4.3 physiological function the enzyme reacts to environmental stresses such as phosphate deficiency and aluminium toxicity, and has a role in root development and brassinolide signalling, role for NPC4 in the response of Arabidopsis to salt stress, overview Arabidopsis thaliana