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Literature summary extracted from

  • Stierl, M.; Stumpf, P.; Udwari, D.; Gueta, R.; Hagedorn, R.; Losi, A.; Gaertner, W.; Petereit, L.; Efetova, M.; Schwarzel, M.; Oertner, T.G.; Nagel, G.; Hegemann, P.
    Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa (2011), J. Biol. Chem., 286, 1181-1188.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.6.1.1 expressed in Escherichia coli strains BL21 (DE3) and BTH101, in Xenopus laevis oocytes, rat hippocampal pyramidal cells, and in the Drosophila melanogaster central nervous system Beggiatoa sp.

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.1 Beggiatoa sp.
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.6.1.1 Co2+-NTA column chromatography Beggiatoa sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.1 ATP
-
 Beggiatoa sp. 3',5'-cyclic-AMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.6.1.1 bacterial photoactivated adenylyl cyclase
-
 Beggiatoa sp.
4.6.1.1 bPAC
-
 Beggiatoa sp.

Cofactor

EC Number Cofactor Comment Organism Structure
4.6.1.1 Calmodulin
-
 Beggiatoa sp.

Expression

EC Number Organism Comment Expression
4.6.1.1 Beggiatoa sp. photoactivated adenylyl cyclase activity is increased 300fold in the light up