BRENDA - Enzyme Database

Phospholipase C activity affinity purifies with the Torpedo nicotinic acetylcholine receptor

Labriola, J.M.; daCosta, C.J.; Wang, S.; Figeys, D.; Smith, J.C.; Sturgeon, R.M.; Baenziger, J.E.; J. Biol. Chem. 285, 10337-10343 (2010)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.3
additional information
no inhibition by N-ethylmaleimide
Tetronarce californica
3.1.4.3
Sodium vanadate
a lipid phosphate phosphohydrolase inhibitor
Tetronarce californica
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.4.3
Tetronarce californica
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.3
phosphatidic acid + H2O
specific for
715502
Tetronarce californica
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.3
additional information
no inhibition by N-ethylmaleimide
Tetronarce californica
3.1.4.3
Sodium vanadate
a lipid phosphate phosphohydrolase inhibitor
Tetronarce californica
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.3
phosphatidic acid + H2O
specific for
715502
Tetronarce californica
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
3.1.4.3
physiological function
a phospholipase C activity, which appears to be specific for phosphatidic acid, is associated with the nicotinic acetylcholine receptor. The acetylcholine receptor may directly or indirectly influence lipid metabolism in a manner that enhances its own function
Tetronarce californica
General Information (protein specific)
EC Number
General Information
Commentary
Organism
3.1.4.3
physiological function
a phospholipase C activity, which appears to be specific for phosphatidic acid, is associated with the nicotinic acetylcholine receptor. The acetylcholine receptor may directly or indirectly influence lipid metabolism in a manner that enhances its own function
Tetronarce californica