EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.315 | microsome | - |
Bos taurus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.1.1.315 | 32000 | - |
x * 32000, SDS-PAGE | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.315 | 11-cis-retinol-[cellular retinaldehyde binding protein] + NAD+ | Bos taurus | - |
11-cis-retinal-[cellular retinaldehyde binding protein] + NADH + H+ | - |
? | |
1.1.1.315 | 11-cis-retinol-[cellular retinaldehyde binding protein] + NADP+ | Bos taurus | - |
11-cis-retinal-[cellular retinaldehyde binding protein] + NADPH + H+ | - |
? | |
1.1.1.315 | additional information | Bos taurus | cRDH does not react with endogenous all-trans-retinal bound to retinal G protein-coupled receptor RGR but reacts specifically with 11-cis-retinal that is generated by photoisomerization after irradiation of RGR. The reduction of 11-cis-retinal to 11-cis-retinol by cRDH enhances the net photoisomerization of all-trans-retinal bound to RGR | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.315 | Bos taurus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.315 | enzyme copurifies with retinal G protein coupled receptor from microsomes | Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.315 | retina | - |
Bos taurus | - |
1.1.1.315 | retinal pigment epithelium | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.315 | 11-cis-retinol-[cellular retinaldehyde binding protein] + NAD+ | - |
Bos taurus | 11-cis-retinal-[cellular retinaldehyde binding protein] + NADH + H+ | - |
? | |
1.1.1.315 | 11-cis-retinol-[cellular retinaldehyde binding protein] + NADP+ | - |
Bos taurus | 11-cis-retinal-[cellular retinaldehyde binding protein] + NADPH + H+ | - |
? | |
1.1.1.315 | additional information | cRDH does not react with endogenous all-trans-retinal bound to retinal G protein-coupled receptor RGR but reacts specifically with 11-cis-retinal that is generated by photoisomerization after irradiation of RGR. The reduction of 11-cis-retinal to 11-cis-retinol by cRDH enhances the net photoisomerization of all-trans-retinal bound to RGR | Bos taurus | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.1.1.315 | ? | x * 32000, SDS-PAGE | Bos taurus |
1.1.1.315 | More | enzyme copurifies with retinal G protein coupled receptor from microsomes | Bos taurus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.315 | cRDH | - |
Bos taurus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.315 | NAD+ | NAD+ is preferred over NADP+ | Bos taurus | |
1.1.1.315 | NADP+ | NAD+ is preferred over NADP+ | Bos taurus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.1.1.315 | physiological function | cRDH is involved in the processing of 11-cis-retinal after irradiation of retinal G protein-coupled receptor RGR opsin and plays a role in the visual cycle | Bos taurus |