EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.3.74 | Mg2+ | required | Botrytis cinerea |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.3.74 | Botrytis cinerea | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.74 | (2E,6E)-farnesyl diphosphate + H2O | - |
Botrytis cinerea | presilphiperfolan-8beta-ol + diphosphate | - |
? | |
4.2.3.74 | additional information | the conversion of (2E,6E)-farnesyl diphosphate to presilphiperfolan-8beta-ol involves initial formation of the humulyl cation which then cyclizes to the 2-epicaryophyllenyl ion. Following ring expansion and further cyclization, the resultant tricyclic cation undergoes a 1,3-hydride shift to generate the presilphiperfolan-8-yl cation which is then quenched by capture of water to give presilphiperfolan-8beta-ol | Botrytis cinerea | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.3.74 | BOT2 | - |
Botrytis cinerea |
4.2.3.74 | PSPS | - |
Botrytis cinerea |
EC Number | General Information | Comment | Organism |
---|---|---|---|
4.2.3.74 | malfunction | inactivation of the BOT2 gene results in strain-dependent loss of virulence | Botrytis cinerea |
4.2.3.74 | metabolism | the BOT2 gene encodes the sesquiterpene synthase that is responsible for the committed step in the biosynthesis of botrydial | Botrytis cinerea |