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Literature summary extracted from
- Immunization of mice with recombinant S-adenosyl-L-homocysteine hydrolase protein confers protection against Brucella melitensis infection (2011), FEMS Immunol. Med. Microbiol., 61, 159-167.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.13.2.1 | medicine | identification of 27 immunogenic proteins from the two-dimensional electrophoresis immunoblot profiles by liquid chromatography tandem MS and expression of the gene encoding one immunodominant protein of interest, S-adenosyl-L-homocysteine hydrolase in Escherichia coli. The recombinant protein induces a strong antibody response in BALB/c mice, and the polyclonal antibody recognizes a band of approximately 52 kDa in the immunoblots of soluble protein extracts from five Brucella strains. The recombinant protein significantly stimulates the production of interferon-gamma and interleukin-2, and induces a high level of protection against Brucella melitensis 16M challenge at 4 weeks postchallenge | Brucella melitensis |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.13.2.1 | expression in Escherichia coli | Brucella melitensis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.13.2.1 | Brucella melitensis | - |
- |
- |
| 3.13.2.1 | Brucella melitensis 16M | - |
- |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.13.2.1 | AdoHcyase | - |
Brucella melitensis |
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Release 2023.1 (January 2023)
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