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Literature summary extracted from
- Phosphorylation is the major mechanism regulating isocitrate lyase activity in Paracoccidioides brasiliensis yeast cells (2011), FEBS J., 278, 2318-2332.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 4.1.3.1 | a thioredoxin/His-tagged version expressed in Escherichia coli BL21(DE3) | Paracoccidioides brasiliensis |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | 60000 | - |
x * 60000, SDS-PAGE | Paracoccidioides brasiliensis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.3.1 | Paracoccidioides brasiliensis | Q5YLB6 | - |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | phosphoprotein | inactivation by phosphorylation | Paracoccidioides brasiliensis |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.3.1 | immobilized metal ion affinity chromatography (Ni2+), tags removed | Paracoccidioides brasiliensis |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | 3.85 | - |
pH and temperature not specified in the publication | Paracoccidioides brasiliensis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.1 | isocitrate | - |
Paracoccidioides brasiliensis | glyoxylate + succinate | - |
? |  |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | ? | x * 60000, SDS-PAGE | Paracoccidioides brasiliensis |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | isocitrate lyase | - |
Paracoccidioides brasiliensis |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 4.1.3.1 | Paracoccidioides brasiliensis | predicted | - |
6.79 |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | metabolism | glyoxylate cycle key enzyme | Paracoccidioides brasiliensis |
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Release 2023.1 (January 2023)
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