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Literature summary extracted from

  • Theissen, U.; Martin, W.
    Sulfide:quinone oxidoreductase (SOR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity (2008), FEBS J., 275, 1131-1139.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.8.5.4 cyanide SQR isolated from yeast mitochondria reduces decyl-ubiquinone after the addition of sulfide only in the presence of cyanide Arenicola marina

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.8.5.4 expressed in Saccharomyces cerevisiae Arenicola marina

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.5.4 antimycin A competitive inhibition Arenicola marina
1.8.5.4 cyanide substrate inhibition Arenicola marina

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.5.4 0.0064
-
 decylubiquinone 20 mM Tris-HCl, pH 8.0, at 22°C Arenicola marina
1.8.5.4 0.23
-
 Sulfide 20 mM Tris-HCl, pH 8.0, at 22°C Arenicola marina
1.8.5.4 2.6
-
 cyanide 20 mM Tris-HCl, pH 8.0, at 22°C Arenicola marina

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.5.4 mitochondrial membrane
-
 Arenicola marina 31966
-

Organism

EC Number Organism UniProt Comment Textmining
1.8.5.4 Arenicola marina
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.5.4 Ni-NTA column chromatography Arenicola marina

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.5.4 sulfide + decylubiquinone + cyanide
-
 Arenicola marina sulfur + decylubiquinol + thiocyanate
-
 ?
1.8.5.4 sulfide + decylubiquinone + Escherichia coli thioredoxin with Escherichia coli thioredoxin, SQR exhibits one-tenth of the cyanide-dependent activity Arenicola marina sulfur + decylubiquinol + ?
-
 ?
1.8.5.4 sulfide + decylubiquinone + sulfite with sulfite, SQR exhibits one-tenth of the cyanide-dependent activity Arenicola marina sulfur + decylubiquinol + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.5.4 SQR
-
 Arenicola marina
1.8.5.4 sulfide:quinone oxidoreductase
-
 Arenicola marina

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.8.5.4 9
-
-
 Arenicola marina

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.5.4 FAD
-
 Arenicola marina

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.8.5.4 0.7
-
 cyanide 20 mM Tris-HCl, pH 8.0, at 22°C Arenicola marina