EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.3.99.2 | N-methoxy-N-methyl-4-(5-benzoylbenzimidazole-2-yl)-3,5-dimethylpyrrole-2-carboxamide | TAS-204, specific H-PGDS inhibitor | Cavia porcellus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.2 | Prostaglandin H2 | Cavia porcellus | - |
Prostaglandin D2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.2 | Cavia porcellus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
5.3.99.2 | nasal mucosa | - |
Cavia porcellus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.2 | Prostaglandin H2 | - |
Cavia porcellus | Prostaglandin D2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.2 | H-PGDS | - |
Cavia porcellus |
5.3.99.2 | Hematopoietic prostaglandin D synthase | - |
Cavia porcellus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
5.3.99.2 | physiological function | H-PGDS plays a critical role in the development of allergic rhinitis, especially in the induction of late phase nasal obstruction | Cavia porcellus |