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Literature summary extracted from

  • Kawasaki, M.; Miura, Y.; Yagasaki, K.
    Effects of sulfur amino acids, L-methionine, L-cystine and L-cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes (2010), Cytotechnology, 62, 225-233.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.79 L-methionine L-methionine enhances the enzyme activity in absence of tumor necrosis factor-alpha, but inhibits it in presence of TNF-alpha Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.79 L-cysteine inhibits the enzyme activity in presence of TNF-alpha Mus musculus
3.1.1.79 L-cystine inhibits the enzyme activity in presence of TNF-alpha Mus musculus
3.1.1.79 L-methionine L-methionine enhances the enzyme activaty in absence of tumor necrosis factor-alpha, but inhibits it in presence of TNF-alpha Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.79 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.79 3T3-L1 cell
-
 Mus musculus
-
3.1.1.79 adipocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.79 triolein + H2O
-
 Mus musculus diolein + oleate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.79 HSL
-
 Mus musculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.79 37
-
 assay at Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.79 8
-
 assay at Mus musculus

Expression

EC Number Organism Comment Expression
3.1.1.79 Mus musculus tumor necrosis factor-alpha suppresses the enzyme down