Literature summary extracted from

Kovarik, Z.; Katalinic, M.; Sinko, G.; Binder, J.; Holas, O.; Jung, Y.; Musilova, L.; Jun, D.; Kuca, K.
Pseudo-catalytic scavenging: Searching for a suitable reactivator of phosphorylated butyrylcholinesterase (2010), Chem. Biol. Interact., 187, 167-171.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.1.8	paraoxon	-	Homo sapiens
3.1.1.8	Tabun	the most potent reactivators of tabun-inhibited BChE are 1,1'-(2,2'-oxybis(ethane-2,1-diyl))bis(4-hydroxyiminomethyl pyridinium) bromide and 4-carbamoyl-1-(2-(2-(4-(hydroxyiminomethyl)pyridinium-1-yl)ethoxy)ethyl)pyridinium bromide. Reactivation by these oximes (1 mM) reaches about 50% of control activity after 20 min, however, reactivation stops at 70%	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.1.8	Homo sapiens	P06276	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.1.8	blood plasma	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.1.8	butyrylthiocholine + H2O	-	Homo sapiens	thiocholine + butyrate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.1.1.8	BChE	-	Homo sapiens
3.1.1.8	butyrylcholinesterase	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)