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Literature summary extracted from

  • Ray, S.; Chen, Y.; Ayoung, J.; Hanna, R.; Brazill, D.
    Phospholipase D controls Dictyostelium development by regulating G protein signaling (2011), Cell. Signal., 23, 335-343.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
3.1.4.4 additional information construction of a pldB disruption mutant by nucleotide replacement Dictyostelium discoideum

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.4 Dictyostelium discoideum
-
 gene pldB
-
3.1.4.4 Dictyostelium discoideum AX3
-
 gene pldB
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.4 phosphatidylcholine + H2O a phospholipid transphosphatidylation reaction Dictyostelium discoideum phosphatidic acid + choline
-
 ?
3.1.4.4 phosphatidylcholine + H2O a phospholipid transphosphatidylation reaction Dictyostelium discoideum AX3 phosphatidic acid + choline
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.4 PldB
-
 Dictyostelium discoideum

General Information

EC Number General Information Comment Organism
3.1.4.4 malfunction cells lacking PldB preferentially sort to the stalk in chimeric fruiting bodies with wild-type cells Dictyostelium discoideum
3.1.4.4 metabolism PldB mediates quorum sensing in the CMF pathway and regulates the dissociation of G protein Galpha2betagamma Dictyostelium discoideum
3.1.4.4 physiological function PldB regulates cAMP chemotaxis, overview. Phospholipase D controls Dictyostelium development by regulating G protein signaling, its activity is required for CMF to alter the kinetics of cAMP-induced G protein signaling, overview Dictyostelium discoideum