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Literature summary extracted from

  • Mohd-Pahmi, S.H.; Hussein, W.M.; Schenk, G.; McGeary, R.P.
    Synthesis, modelling and kinetic assays of potent inhibitors of purple acid phosphatase (2011), Bioorg. Med. Chem. Lett., 21, 3092-3094.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.2 [(butanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Phaseolus vulgaris
3.1.3.2 [(butanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Sus scrofa
3.1.3.2 [(decanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Phaseolus vulgaris
3.1.3.2 [(decanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Sus scrofa
3.1.3.2 [(dodecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Phaseolus vulgaris
3.1.3.2 [(dodecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Sus scrofa
3.1.3.2 [(heptanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Phaseolus vulgaris
3.1.3.2 [(heptanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Sus scrofa
3.1.3.2 [(hexadecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Phaseolus vulgaris
3.1.3.2 [(hexadecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid
-
 Sus scrofa
3.1.3.2 [naphthalen-1-yl(octanoylamino)methyl]phosphonic acid
-
 Phaseolus vulgaris
3.1.3.2 [naphthalen-1-yl(octanoylamino)methyl]phosphonic acid
-
 Sus scrofa
3.1.3.2 [naphthalen-1-yl(tetradecanoylamino)methyl]phosphonic acid
-
 Phaseolus vulgaris
3.1.3.2 [naphthalen-1-yl(tetradecanoylamino)methyl]phosphonic acid
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.2 Phaseolus vulgaris
-
-
-
3.1.3.2 Sus scrofa
-
-
-

Synonyms

EC Number Synonyms Comment Organism
3.1.3.2 acid phosphatase
-
 Sus scrofa
3.1.3.2 PAP
-
 Sus scrofa
3.1.3.2 rkbPAP red kidney bean PAP Phaseolus vulgaris

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.3.2 0.005
-
 [(dodecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Phaseolus vulgaris
3.1.3.2 0.008
-
 [naphthalen-1-yl(tetradecanoylamino)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Sus scrofa
3.1.3.2 0.01
-
 [(decanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Sus scrofa
3.1.3.2 0.011
-
 [naphthalen-1-yl(tetradecanoylamino)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Phaseolus vulgaris
3.1.3.2 0.013
-
 [(hexadecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Sus scrofa
3.1.3.2 0.021
-
 [(dodecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Sus scrofa
3.1.3.2 0.031
-
 [(hexadecanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Phaseolus vulgaris
3.1.3.2 0.044
-
 [naphthalen-1-yl(octanoylamino)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Sus scrofa
3.1.3.2 0.057
-
 [(decanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Phaseolus vulgaris
3.1.3.2 0.116
-
 [(heptanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Sus scrofa
3.1.3.2 0.195
-
 [naphthalen-1-yl(octanoylamino)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Phaseolus vulgaris
3.1.3.2 0.222
-
 [(heptanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Phaseolus vulgaris
3.1.3.2 0.238
-
 [(butanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Phaseolus vulgaris
3.1.3.2 0.363
-
 [(butanoylamino)(naphthalen-1-yl)methyl]phosphonic acid pH 4.9, competitive inhibition constant, temperature not specified in the publication Sus scrofa