EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
7.1.1.3 | F112L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F113L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F208L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F295L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F336L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F347L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F348L | 4.8% activity compared to the wild type enzyme | Escherichia coli |
7.1.1.3 | F391L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F415W | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | F420L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | W147L | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | W280L | 67% activity compared to the wild type enzyme | Escherichia coli |
7.1.1.3 | W282F | the mutation does not affect the in vivo activity | Escherichia coli |
7.1.1.3 | W331L | 19% activity compared to the wild type enzyme | Escherichia coli |
7.1.1.3 | Y288L | 0.3% activity compared to the wild type enzyme | Escherichia coli |
7.1.1.3 | Y61F | the mutation does not affect the in vivo activity | Escherichia coli |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
7.1.1.3 | Cu2+ | the enzyme contains 6.78 nmol copper per mg of protein | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.1.1.3 | Escherichia coli | - |
- |
- |
7.1.1.3 | Escherichia coli GO103/pMFO2 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.1.1.3 | ubiquinol + O2 + H+/in | - |
Escherichia coli | ubiquinone + H2O + H+/out | - |
? | |
7.1.1.3 | ubiquinol + O2 + H+/in | - |
Escherichia coli GO103/pMFO2 | ubiquinone + H2O + H+/out | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
7.1.1.3 | tetramer | - |
Escherichia coli |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.1.1.3 | bo-type ubiquinol oxidase | - |
Escherichia coli |
7.1.1.3 | cytochrome bo | - |
Escherichia coli |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
7.1.1.3 | heme | low-spin heme b and high-spin heme o | Escherichia coli |
EC Number | General Information | Comment | Organism |
---|---|---|---|
7.1.1.3 | physiological function | cytochrome bo is a four-subunit quinol oxidase in the aerobic respiratory chain of Escherichia coli and functions as a redox-coupled proton pump | Escherichia coli |