Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Drayer, A.; Pesesse, X.; De Smedt, F.; Communi, D.; Moreau, C.; Erneux, C.
    The family of inositol and phosphatidylinositol polyphosphate 5-phosphatases (1996), Biochem. Soc. Trans., 24, 1001-1005.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.3.86 expressed in COS-7 cells Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.86 additional information the enzyme is insensitive to N-ethylmaleimide, InsPh and 2,3-bisphosphoglycerate Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.86 145000
-
 gel filtration Homo sapiens
3.1.3.86 145000
-
 gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.86 Homo sapiens
-
-
-
3.1.3.86 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.86 brain
-
 Homo sapiens
-
3.1.3.86 brain
-
 Rattus norvegicus
-
3.1.3.86 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.86 1-phosphatidyl-1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Homo sapiens 1-phosphatidyl-1D-myo-inositol 1,3,4-trisphosphate + phosphate
-
 ?
3.1.3.86 1-phosphatidyl-1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Rattus norvegicus 1-phosphatidyl-1D-myo-inositol 1,3,4-trisphosphate + phosphate
-
 ?
3.1.3.86 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O
-
 Homo sapiens 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?
3.1.3.86 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O
-
 Rattus norvegicus 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.86 PtdIns(3,4,5)P3 5-phosphatase
-
 Homo sapiens
3.1.3.86 PtdIns(3,4,5)P3 5-phosphatase
-
 Rattus norvegicus
3.1.3.86 SH2 domain containing 5-phosphatase
-
 Homo sapiens
3.1.3.86 SHIP
-
 Homo sapiens