EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.22 | S-adenosyl-L-methionine | - |
Saccharomyces cerevisiae | |
4.2.1.22 | S-adenosyl-L-methionine | - |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.22 | L-serine + L-homocysteine | Aeropyrum pernix | - |
L-cystathionine + H2O | - |
? | |
4.2.1.22 | L-serine + L-homocysteine | Saccharomyces cerevisiae | - |
L-cystathionine + H2O | - |
? | |
4.2.1.22 | L-serine + L-homocysteine | Homo sapiens | - |
L-cystathionine + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.22 | Aeropyrum pernix | Q9YCN5 | cystathionine beta-synthase | - |
4.2.1.22 | Homo sapiens | P35520 | - |
- |
4.2.1.22 | Saccharomyces cerevisiae | P32582 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.22 | L-serine + L-homocysteine | - |
Aeropyrum pernix | L-cystathionine + H2O | - |
? | |
4.2.1.22 | L-serine + L-homocysteine | - |
Saccharomyces cerevisiae | L-cystathionine + H2O | - |
? | |
4.2.1.22 | L-serine + L-homocysteine | - |
Homo sapiens | L-cystathionine + H2O | - |
? | |
4.2.1.22 | additional information | O-acetylserine sulfhydrylase isozyme A, OASSAp, EC 2.5.1.65, exhibits both O-acetylserine sulfhydrylase and cystathionine beta-synthase activities | Aeropyrum pernix | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.2.1.22 | multimer | - |
Saccharomyces cerevisiae |
4.2.1.22 | multimer | - |
Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.22 | CBS | - |
Aeropyrum pernix |
4.2.1.22 | CBS | - |
Saccharomyces cerevisiae |
4.2.1.22 | CBS | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.22 | heme | - |
Saccharomyces cerevisiae | |
4.2.1.22 | heme | - |
Homo sapiens | |
4.2.1.22 | pyridoxal 5'-phosphate | - |
Aeropyrum pernix | |
4.2.1.22 | pyridoxal 5'-phosphate | - |
Saccharomyces cerevisiae | |
4.2.1.22 | pyridoxal 5'-phosphate | - |
Homo sapiens |
EC Number | General Information | Comment | Organism |
---|---|---|---|
4.2.1.22 | metabolism | CBS is involved in the cysteine pathway of bacteria and plants, overview | Saccharomyces cerevisiae |
4.2.1.22 | metabolism | CBS is involved in the cysteine pathway of bacteria and plants, overview | Homo sapiens |
4.2.1.22 | metabolism | cystathionine beta-synthase is involved in the cysteine pathway of bacteria and plants, overview | Aeropyrum pernix |