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Literature summary extracted from

  • Sugano, Y.; Lai, N.C.; Gao, M.H.; Firth, A.L.; Yuan, J.X.; Lew, W.Y.; Hammond, H.K.
    Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart (2011), Biochem. Biophys. Res. Commun., 405, 349-355.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.1 Mus musculus
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-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.6.1.1 heart
-
 Mus musculus
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Synonyms

EC Number Synonyms Comment Organism
4.6.1.1 AC6 isoform Mus musculus
4.6.1.1 adenylyl cyclase 6 isoform Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
4.6.1.1 Calmodulin
-
 Mus musculus

General Information

EC Number General Information Comment Organism
4.6.1.1 physiological function cardiac-directed adenylyl cyclase 6 expression attenuates left ventricular hypertrophy and dysfunction in cardiomyopathy. Left ventricular contractility is increased, diastolic function is improved and left ventricular dilation is reduced by activation of adenylyl cyclase 6 expression Mus musculus