Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Astecker, N.; Bobrovnikova, E.A.; Omdahl, J.L.; Gennaro, L.; Vouros, P.; Schuster, I.; Uskokovic, M.R.; Ishizuka, S.; Wang, G.; Reddy, G.S.
    C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1 (2004), Arch. Biochem. Biophys., 431, 261-270.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.14.15.16 Homo sapiens
-
-
-
1.14.15.16 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.15.16
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.15.16 keratinocyte neonatal foreskin keratinocyte Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.15.16 1alpha,24(R)-dihydroxyvitamin D3 + NADPH + H+ + O2 i.e. tacalcitol, hydroxylation occurs at C-25 Homo sapiens ?
-
 ?
1.14.15.16 1alpha,24(R)-dihydroxyvitamin D3 + NADPH + H+ + O2 i.e. tacalcitol, hydroxylation occurs at C-25 Rattus norvegicus ?
-
 ?
1.14.15.16 1alpha,25-dihydroxyvitamin D3 + NADPH + H+ + O2 1alpha,25-dihydroxyvitamin D3 is calcitriol Homo sapiens 1alpha,24(R)-dihydroxyvitamin D3 + NADP+ + H2O
-
 ?
1.14.15.16 1alpha,25-dihydroxyvitamin D3 + NADPH + H+ + O2 1alpha,25-dihydroxyvitamin D3 is calcitriol Rattus norvegicus 1alpha,24(R)-dihydroxyvitamin D3 + NADP+ + H2O
-
 ?
1.14.15.16 25-hydroxyvitamin D3 + NADPH + H+ + O2
-
 Homo sapiens 24R,25-dihydroxyvitamin D3 + NADP+ + H2O
-
 ?
1.14.15.16 25-hydroxyvitamin D3 + NADPH + H+ + O2
-
 Rattus norvegicus 24R,25-dihydroxyvitamin D3 + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.15.16 25-hydroxyvitamin D3-24-hydroxylase
-
 Homo sapiens
1.14.15.16 25-hydroxyvitamin D3-24-hydroxylase
-
 Rattus norvegicus
1.14.15.16 CYP24A1
-
 Homo sapiens
1.14.15.16 CYP24A1
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.15.16 NADPH
-
 Homo sapiens
1.14.15.16 NADPH
-
 Rattus norvegicus