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Literature summary extracted from

  • Umbach, A.L.; Siedow, J.N.
    The cyanide-resistant alternative oxidases from the fungi Pichia stipitis and Neurospora crassa are monomeric and lack regulatory features of the plant enzyme (2000), Arch. Biochem. Biophys., 378, 234-245.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.10.3.11 ADP
-
 Neurospora crassa
1.10.3.11 ADP
-
 Scheffersomyces stipitis
1.10.3.11 GMP GMP (0.25 mM) is a strong activator Neurospora crassa
1.10.3.11 GMP GMP (0.25 mM) is a strong activator Scheffersomyces stipitis
1.10.3.11 additional information alternative oxidase activity is not stimulated by pyruvate and glyoxylate. Pyruvate does only stimulate activity when succinate is the respiratory substrate but this is not a direct effect on the alternative oxidase Neurospora crassa
1.10.3.11 additional information alternative oxidase activity is not stimulated by pyruvate and glyoxylate. Pyruvate does only stimulate activity when succinate is the respiratory substrate but this is not a direct effect on the alternative oxidase Scheffersomyces stipitis
1.10.3.11 pyruvate
-
 Neurospora crassa
1.10.3.11 pyruvate
-
 Scheffersomyces stipitis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.10.3.11 mitochondrion
-
 Neurospora crassa 5739
-
1.10.3.11 mitochondrion
-
 Scheffersomyces stipitis 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.10.3.11 36000
-
 1 * 36000, SDS-PAGE Neurospora crassa
1.10.3.11 36000
-
 1 * 36000, SDS-PAGE Scheffersomyces stipitis

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.11 Neurospora crassa
-
-
-
1.10.3.11 Scheffersomyces stipitis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.11 duroquinol + O2
-
 Neurospora crassa duroquinone + H2O
-
 ?
1.10.3.11 duroquinol + O2
-
 Scheffersomyces stipitis duroquinone + H2O
-
 ?
1.10.3.11 additional information the enzyme is unable to use NADH as respiratory substrate Neurospora crassa ?
-
 ?
1.10.3.11 additional information the enzyme is unable to use NADH as respiratory substrate Scheffersomyces stipitis ?
-
 ?
1.10.3.11 succinate + O2
-
 Neurospora crassa ?
-
 ?
1.10.3.11 succinate + O2
-
 Scheffersomyces stipitis ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.10.3.11 monomer 1 * 36000, SDS-PAGE Neurospora crassa
1.10.3.11 monomer 1 * 36000, SDS-PAGE Scheffersomyces stipitis

Synonyms

EC Number Synonyms Comment Organism
1.10.3.11 cyanide-resistant alternative oxidase
-
 Neurospora crassa
1.10.3.11 cyanide-resistant alternative oxidase
-
 Scheffersomyces stipitis